Computer-based Cognitive Rehabilitation

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Research

We understand how important it is for you to be able to analyse and understand the clinical evidence for cognitive rehabilitation, and in particular, using RehaCom. This site contains a Research overview, and sectioned list of abstracts and links for the different clinical applications of RehaCom.


Traumatic brain injury (TBI)

Can impaired working memory functioning be improved by training? A meta-analysis with a special focus on brain injured patients.
Weicker J1, Villringer A1, Thöne-Otto A2.
Neuropsychology. 2016 Feb;30(2):190-212. doi: 10.1037/neu0000227.

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Working memory training and semantic structuring improves remembering future events, not past events.
Richter KM, Mödden C, Eling P, Hildebrandt H
Neurorehabil Neural Repair. 2015 Jan;29(1):33-40. doi: 10.1177/1545968314527352. Epub 2014 Apr 2.

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Attention remediation following traumatic brain injury in childhood and adolescence.
Galbiati S, Recla M, Pastore V, Liscio M, Bardoni A, Castelli E, Strazzer S. (2009); Neuropsychology. 2009 Jan;23(1):40-9. doi: 10.1037/a0013409.

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Clinical Impact of RehaCom Software for Cognitive Rehabilitation of Patients with Acquired Brain Injury International Neurological Restoration Center (CIREN 2012)
Elízabeth Fernández MS, María Luisa Bringas PhD, Sonia Salazar, Daymí Rodríguez, María Eugenia García MS, Maydané Torres MS; Havana, Cuba im MEDICC Review, October 2012, Vol 14, No 4

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Effectiveness of Cognitive Rehabilitation Following Acquired Brain Injury: A Meta-Analytic Re-Examination of Cicerone et al.’s (2000, 2005)
Martin L. Rohling, Mark E. Faust, Brenda Beverly, George Demakis (2009); Systematic Reviews. © 2009 American Psychological Association, 2009, Vol. 23, No. 1, 20–39

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Evidence-based cognitive rehabilitation: updated review of the literature from 1998 through 2002.
Cicerone KD, Dahlberg C, Malec JF, Langenbahn DM, Felicetti T, Kneipp S, Ellmo W, Kalmar K, Giacino JT, Harley JP, Laatsch L, Morse PA, Catanese J.
Arch Phys Med Rehabil. 2005 Aug;86(8):1681-92.Go to Study »


Stroke

Effects of neurofeedback and computer-assisted cognitive rehabilitation on relative brain wave ratios and activities of daily living of stroke patients: a randomized control trial
Hwi-Young Cho, PhD, PT, Ki-Tae Kim, PhD, KMD, and Jin-Hwa Jung, PhD, OT
J Phys Ther Sci. 2016 Jul; 28(7): 2154–2158

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Recovery after brain damage: Is there any indication for generalization between different cognitive functions?
Richter KM, Mödden C, Hanken K, Hildebrandt H.
J Clin Exp Neuropsychol. 2015;37(6):571-80. doi: 10.1080/13803395.2015.1030358. Epub 2015 Jun 10.

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Effect of computerized cognitive rehabilitation program on cognitive function and activities of living in stroke patients
Chanuk Yoo, Mi-hyun Yong, Jaeyeop Chung, and Yeongae Yang, J Phys Ther Sci. 2015 Aug; 27(8): 2487–2489.

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Clinical Efficacy of Acupuncture Treatment in Combination With RehaCom Cognitive Training for Improving Cognitive Function in Stroke: A 2 × 2 Factorial Design Randomized Controlled Trial
Cai Jiang, Shanli Yang, Jing Tao, Jia Huang, Yinyan Li, Haicheng Ye, Shanjia Chen, Wenjun Hong, Lidian Chen
December 1, 2016 Volume 17, Issue 12, Pages 1114–1122

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A Randomized Controlled Trial Comparing 2 Interventions for Visual Field Loss With Standard Occupational Therapy During Inpatient Stroke Rehabilitation
Mödden C, Behrens M, Damke I, Eilers N, Kastrup A, Hildebrandt H.
Neurorehabil Neural Repair. 2012 Jun;26 (5):463-9. doi: 10.1177/1545968311425927. Epub 2011 Dec 2.

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Dementia/Alzheimer

A randomised pilot study to assess the efficacy of an interactive, multimedia tool of cognitive stimulation in Alzheimer’s disease.
Tárraga L, Boada M, Modinos G, Espinosa A, Diego S, Morera A, Guitart M, Balcells J, López OL, Becker JT (2006); Journal Neurol Neurosurg Psychiatry 2006 Oct;77(10):1116-21. Epub 2006 Jul 4.

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The Effects of Cognitive Rehabilitation Training on Cognitive Function of Elderly Dementia Patients
Byoung-Hoon Oh, MD, Young-Kee Kim, MD, Ji-Hye Kim, MA and Yoon-Sik Shin, MD
J Korean Neuropsychiatr. Assoc. 2003, Vol 42, No 4, 514-519

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ADHD

Evaluation of a computer-based neuropsychological training in children with attention-deficit hyperactivity disorder (ADHD)
Amonn F,Frölich J,Breuer D,Banaschewski T,Doepfner M. 2013, NeuroRehabilitation 32(3):555-62. doi: 10.3233/NRE-130877.

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The efficacy of cognitive training programs in children and adolescents: a meta-analysis.
Karch D, Albers L, Renner G, Lichtenauer N, von Kries R. 2013, Dtsch Arztebl Int. 2013 Sep;110(39):643-52. doi: 10.3238/arztebl.2013.0643. Epub 2013 Sep 27.

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Multiple Sclerosis

A Randomised Controlled Trial of Efficacy of Cognitive Rehabilitation in Multiple Sclerosis: A Cognitive, Behavioural, and MRI Study
J.Campbell, D.Langdon, M.Cercignani, and W.Rashid
Hindawi Publishing Corporation Neural Plasticity Volume 2016, Article ID 4292585, 9 pages


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Cognitive Rehabilitation in Multiple Sclerosis: The Role of Plasticity
Nancy D. Chiaravalloti, Helen M. Genova, and John DeLuca
Front Neurol. 2015; 6: 67. Published online 2015 Apr 2.  doi:  10.3389/fneur.2015.00067

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Computer-Assisted Cognitive Rehabilitation of Attention Deficits for Multiple Sclerosis: A Randomized Trial With fMRI Correlates. Neurorehabil Neural Repair.
Cerasa A, Gioia MC, Valentino P, Nisticò R, Chiriaco C, Pirritano D, Tomaiuolo F, Mangone G, Trotta M, Talarico T, Bilotti G, Quattrone A. 2013 May;27(4):284-95. doi: 10.1177/1545968312465194. Epub 2012 Nov 27.

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Cognitive Rehabilitation in Multiple Sclerosis
Filipa Barbosa, Cláudia Sousa, Luís Nogueira-Silva, Maria José Sá; Sinapse, Vol. 11, No. 1, May 2011

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Efficacy and Specificity of intensive cognitive Rehabilitation of Attention and executive Functions in Multiple Sclerosis
Mattioli F, Stampatori C, Zanotti D, Parrinello G, Capra R.
J Neurol Sci. 2010 Jan 15;288(1-2):101-5. doi: 10.1016/j.jns.2009.09.024. Epub 2009 Oct 13.

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Schizophrenia

The effectiveness of computerized cognitive rehabilitation training program in improving cognitive abilities of schizophrenia clients.
Mohammadi MR, Keshavarzi Z, Talepasand S
Iran J Psychiatry. 2014 Oct;9(4):209-15.

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The efficacy of cognitive neurorehabilitation with RehaCom program in schizophrenia patients.
Mak M, Tybura P, Bieńikowski P, Karakiewicz B, Samochowiec J.
Psychiatr Pol. 2013 Mar-Apr;47(2):213-23.

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A randomized, controlled trial of computer-assisted cognitive remediation for schizophrenia
Thierry d´Amato et. al. in Schizophrenia Research 125 (2011) 284-290

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How can cognitive remediation therapy modulate brain activations in schizophrenia?
An fMRI study.

Julie Bor et. al. 2011; Neuroimaging 192 (2011) 160-166

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Efficacy and specificity of computer-assisted cognitive remediation in schizophrenia: a meta-analytical study.
O. Grynszpan, S. Perbal, A. Pelissolo, P. Fossati1, R. Jouvent1, S. Dubal, F. Perez-Diaz 2010; Psychological Medicine, Page 1 of 11. f Cambridge University Press 2010

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Depressions

Efficacy of Neurocognitive Remediation Therapy During an Acute Depressive Episode and Following Remission: Results From Two Randomised Pilot Studies
M. Semkovska, E. Ahern, D.O. Lonargáin, S. Lambe, D.M. McLaughlin
March 28–31, 2015, Volume 30, Supplement 1, Page 403

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Other

Is the Neuropsychological Treatment of Memory Specific or Unspecific? – Comparing Treatment Effects on Memory and Attention.
Spahn, V., Kulke, H., Kunz, M., Thöne-Otto, A., Schupp, W., Lautenbacher, S. Source, 2010; Zeitschrift für Neuropsychologie , 21 (4),  2010, 239-245

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Neuropsychologie in der beruflichen Rehabilitation: ein neues Interventionsfeld?
Müller S.V., Klaue U., Specht A., Schulz P. 2007; Rehabilitation (Stuttg). 2007 Apr;46(2):93-101.

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Memory enhancement in healthy older adults using a brain plasticity-based training program: A randomized, controlled study.
Mahncke HW, Connor BB, Appelman J, Ahsanuddin ON, Hardy JL, Wood RA, Joyce NM, Boniske T, Atkins SM, Merzenich MM. 2006; Proc Natl Acad Sci USA. 2006 Aug 15;103(33):12523-8. Epub 2006 Aug 3.

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Evidence-Based Cognitive Rehabilitation: Updated Review of the Literature
From 1998 Through 2002.

Keith D. Cicerone et. al. 2005; Arch Phys Med Rehabil Vol 86, August 2005

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Preliminary study of a rehabilitation program based on attentional processes to treat auditory hallucinations.
López-Luengo B, Muela-Martínez JA. Cogn Neuropsychiatry. 2016 Jul;21(4):315-334

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Acute social stress before the planning phase improves memory performance in a complex real life-related prospective memory task.
Glienke K., Piefke M.; Neurobiol Learn Mem. 2016 Sep;133:171-81. doi: 10.1016/j.nlm.2016.06.025. Epub 2016 Jun 28.

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